Genetics Factors Contributing to Type 2 Diabetes across Ethnicities
نویسندگان
چکیده
منابع مشابه
Prevalence of Type 2 Diabetes Complications and their Contributing Factors in Yazd Province
BACKGROUND: Type 2 diabetes is a common disorder recognized as a major health problem in Iran. Diabetes is a major source of morbidity, mortality and economic cost to society. Diabetic patients are at risk of experiencing macrovascular and microvascular complications of diabetes. The aim of this study was to assess the prevalence of type 2 diabetes complications and their contributing factors. ...
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Objective: Type 2 diabetes (T2D) as a complex disease is the result of genetically heterogeneous factors and environmental issues interaction. Linkage and small-scale candidate gene studies were successful in identification of genetic susceptibilities of monogenic form of diseases. However, they were largely unsuccessful while applying to the more common forms of disease. By designing Genome Wi...
متن کاملGenetics of type 2 diabetes.
Identification and characterization of genetic variants that either cause or predispose to diabetes are a major focus of biomedical research. As of early 2007, the molecular basis of most forms of monogenic diabetes resulting from beta-cell dysfunction is known and, in particular, there has been recent success in delineating the genetic aetiology of neonatal diabetes. Finding genes predisposing...
متن کاملGenetics of type 2 diabetes.
BACKGROUND Type 2 diabetes (T2D) is a complex disorder that is affected by multiple genetic and environmental factors. Extensive efforts have been made to identify the disease-affecting genes to better understand the disease pathogenesis, find new targets for clinical therapy, and allow prediction of disease. CONTENT Our knowledge about the genes involved in disease pathogenesis has increased...
متن کاملRisk Factors Contributing to Type 2 Diabetes and Recent Advances in the Treatment and Prevention
Type 2 diabetes is a serious and common chronic disease resulting from a complex inheritance-environment interaction along with other risk factors such as obesity and sedentary lifestyle. Type 2 diabetes and its complications constitute a major worldwide public health problem, affecting almost all populations in both developed and developing countries with high rates of diabetes-related morbidi...
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ژورنال
عنوان ژورنال: Journal of Diabetes Science and Technology
سال: 2009
ISSN: 1932-2968,1932-2968
DOI: 10.1177/193229680900300412